Dr. Anthony Clarke
University of Guelph
Speech TItle: “ The Importance of Technological Advances for Antibiotic Discovery: Identification of Peptidoglycan O-Acetyltransferases as Potential New Antibiotic Targets in Both Gram-Positive and Gram-Negative Bacteria.“
Professor Anthony J. Clarke obtained his PhD from the University of Waterloo in Chemistry (Biochemistry) in 1983. He joined the University of Guelph in 1986 as an assistant professor after post-doctoral stints at the Carlsberg Research Centre, Copenhagen and the National Research Council, Ottawa. Soon after establishing himself in the academic ranks, he was drawn into the University’s administration and he has served as Departmental Chair, College Dean, Associate V.P. (Research), Dean of Graduate Studies, and Assistant V.P. (Graduate Studies and Program Quality Assurance).
He has also served as a member of provincial and national granting agencies, associate editor of scientific journals, and he is currently Co-Editor of the Canadian Journal of Microbiology. Despite these administrative/service responsibilities, Dr. Clarke has maintained an active research program funded by the National Science and Engineering Council of Canada (NSERC), the Canadian Institutes of Health Research (CIHR) and the Canadian National Centres of Excellence (Glycomics Network) that investigates the mechanism of action of enzymes that function on carbohydrates to identify new targets for antibacterial therapy and to facilitate the production of cellulosic ethanol. Such studies entail determining the structure and function relationship of the enzymes involved in the biosynthesis and degradation of peptidoglycan, in antibiotic resistance, and in cellulose hydrolysis. He is the author of one book, nine book chapters, and over 115 articles in scientific journals.
Prof. Colin Robinson
Professor in Biotechnology
University of Kent, UK
Speech TItle: “ Development of a new method to produce high levels of disulphide bonded biopharmaceuticals and subunit vaccines in E. coli“
Colin Robinson is a Professor in Biotechnology at the University of Kent, UK. His work focuses on the production of biopharmaceuticals in E. coli and he has developed novel strategies to transport folded proteins to the periplasm for ease of purification. His work has expanded to include production of subunit vaccines as part of a UK government programme to develop research collaborations in Thailand and elsewhere in South East Asia. The talk will describe a new process to produce active biopharmaceuticals in E. coli at levels of up to 5g/L culture, and will also cover the aims of the expanding collaboration on subunit vaccine